News Haveli, नई दिल्ली: (Denial of permission for Urs) सुप्रीम कोर्ट ने गुजरात के गिर सोमनाथ (Gir Somnath) में उर्स की अनुमति देने से इनकार कर दिया है। एक याचिका में ध्वस्त की जा चुकी दरगाह (Dargah) पर 1 से 3 फरवरी तक उर्स आयोजित करने की अनुमति मांगी गई थी। सुप्रीम कोर्ट (Supreme Court) के इस फैसले के बाद कई दशकों बाद ऐसा होगा जब सोमनाथ के पास होने वाला उर्स (Urs) आयोजित नहीं होगा। न्यायामूर्ति बीआर गवई और न्यायामूर्ति ऑगस्टीन जॉर्ज मसीह की पीठ ने गुजरात सरकार की ओर से पेश सॉलिसिटर जनरल तुषार मेहता की दलीलों पर गौर किया कि सरकारी जमीन पर मंदिरों समेत सभी अनधिकृत निर्माण को ध्वस्त कर दिया गया है।
मुस्लिम पक्ष के वकील ने जो कहा
मुस्लिम पक्ष के वकील ने कहा कि इस स्थान पर सालों से उर्स होता आया है लेकिन प्रशासन ने अब इजाजत देने से इन्कार कर दिया है। उन्होंने कहा कि इसके लिए दलील दी गई कि वहां पर कोई दरगाह नहीं है। रिकॉर्ड में 1960 तक का जिक्र है और कुछ शर्तों के साथ इजाजत मिलती रही है। 3 दिन तक चलने वाला यह महोत्सव हर साल होता रहा है।
गौरतलब है कि मुस्लिम पक्ष का दावा है कि यह दरगाह वर्ष 1299 से मौजूद है। यह एक संरक्षित स्मारक है लेकिन अब इसे तोड़ दिया गया है।
सॉलिसिटर जनरल की दलील
गुजरात सरकार की तरफ से सॉलिसिटर जनरल तुषार मेहता ने कहा कि 1951 मे यह जमीन सरदार पटेल ट्रस्ट को सौपी जा चुकी है। उस इलाके में सभी धर्मों के जो भी अवैध निर्माण थे उन सबको तोड़ा गया है। इनमें मंदिर भी शामिल हैं। मुख्य मामला अभी हाई कोर्ट मे चल रहा है। भारतीय पुरातत्व सर्वेक्षण (ASI) ने भी कहा है कि यहां कोई संरक्षित ढांचा नहीं है। हाई कोर्ट ने इसके बाद मुस्लिम पक्ष की तरफ से दाखिल की गई अनुमति याचिका को खारिज कर दिया।
सुप्रीम कोर्ट में विभिन्न याचिकाओं पर होनी है सुनवाई
इससे पहले सुप्रीम कोर्ट ने 27 जनवरी 2025 को कहा था कि वह गिर सोमनाथ जिले में बिना पूर्व अनुमति के आवासीय और धार्मिक संरचनाओं को कथित रूप से ध्वस्त करने के लिए गुजरात के अधिकारियों के खिलाफ अवमानना याचिका समेत विभिन्न याचिकाओं पर तीन सप्ताह बाद सुनवाई करेगी।
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Ipamorelin has gained popularity among athletes and bodybuilders as a growth
hormone secretagogue that can enhance muscle growth and recovery.
While it is generally considered safer than other analogues such as GHRP‑2
and GHRP‑6, users should be aware of potential long‑term side effects that may
arise with prolonged use. Understanding these risks, the
basic pharmacology of ipamorelin, and specific symptoms like feeling light‑headed or weak can help individuals make informed decisions about
its use.
Ipamorelin Side Effects
The short‑term side effects of ipamorelin are typically mild and include nausea, flushing,
tingling sensations in extremities, increased appetite, and temporary water
retention. However, long‑term exposure may lead to more persistent or cumulative adverse events:
Hormonal Imbalance – Ipamorelin stimulates the
pituitary gland to release growth hormone (GH) and insulin‑like growth factor‑1 (IGF‑1).
Over time, chronic elevation of GH/IGF‑1 can disturb the
normal endocrine axis, potentially resulting in hypogonadism, decreased libido, or altered thyroid function. These changes may become apparent only after months or years of continuous dosing.
Cardiovascular Effects – Sustained increases in IGF‑1 have been linked to hypertension and left
ventricular hypertrophy in animal studies.
In humans, long‑term users sometimes report elevated resting
heart rates, palpitations, or blood pressure fluctuations
that require medical monitoring.
Metabolic Disturbances – Growth hormone can reduce insulin sensitivity, leading to impaired glucose tolerance or
type 2 diabetes over prolonged periods. Users with a family history of metabolic disorders should be particularly
cautious and may need periodic fasting glucose or HbA1c testing.
Edema and Fluid Retention – Chronic exposure
may cause persistent swelling in the ankles, hands, or
face. This can be uncomfortable and sometimes indicates underlying cardiac or renal issues.
Injection Site Reactions – Frequent injections can lead to lipodystrophy, localized skin irritation, or abscess formation.
While these are usually self‑limited, repeated trauma might necessitate changing
injection sites or consulting a healthcare professional.
Mood and Cognitive Changes – Some users report mood swings, anxiety, or irritability
after long‑term use, possibly related to altered hormone levels.
Persistent psychological symptoms warrant evaluation by a mental
health professional.
Rare but Serious Complications – Though uncommon, there
have been isolated reports of increased risk for certain cancers (particularly breast cancer) due to chronic GH/IGF‑1 stimulation. Longitudinal studies are limited, so the true incidence
remains uncertain.
What is Ipamorelin?
Ipamorelin is a pentapeptide (five amino acids) that functions as a selective
growth hormone secretagogue receptor agonist. Unlike other peptides
in its class, ipamorelin has a high affinity for the ghrelin receptor while sparing the orexin system, which reduces many of the typical side effects seen with older analogues.
The drug is typically administered via subcutaneous injection and acts quickly to increase circulating GH levels by stimulating the pituitary gland.
Key pharmacological characteristics include:
Rapid onset: Peak GH stimulation occurs within 15–30 minutes
after injection.
Short half‑life: Ipamorelin is cleared from the body in about an hour, allowing for flexible dosing
schedules (often twice daily or once before bed).
Selectivity: It does not significantly affect cortisol, prolactin, or thyroid hormone levels under normal conditions.
Safety profile: In controlled trials, ipamorelin has shown minimal
acute toxicity and a low incidence of adverse events compared to other GHSAs.
Because of these properties, many users consider ipamorelin an attractive option for boosting muscle
mass, enhancing recovery, and improving sleep quality.
Nonetheless, the potential long‑term side effects outlined above highlight
the importance of careful monitoring and adherence to recommended dosage guidelines.
Feeling Light‑headed or Weak
One symptom that some individuals experience during or after ipamorelin use is a feeling of light‑headedness or weakness.
This can arise from several underlying mechanisms:
Hypotension – The vasodilatory effects of growth hormone may cause blood pressure to drop,
especially when standing up quickly (orthostatic hypotension).
If the brain receives less oxygenated blood temporarily, users might
feel faint or weak.
Electrolyte Imbalance – Chronic use can lead to
subtle shifts in sodium and potassium levels, particularly
if fluid retention occurs. Low sodium (hyponatremia) may manifest as dizziness,
fatigue, or a general sense of weakness.
Central Nervous System Effects – While ipamorelin is not known to
cross the blood‑brain barrier extensively, altered hormone levels can influence neurotransmitter balance.
Users with pre‑existing migraine or vestibular disorders might notice exacerbated symptoms
such as light‑headedness.
Injection‑Related Issues – If the injection site becomes inflamed or if an accidental intravascular injection occurs, a
brief drop in blood volume could trigger transient weakness
or dizziness.
Managing these sensations involves several practical steps:
Stay hydrated and maintain balanced electrolytes by consuming adequate sodium and potassium.
Monitor blood pressure regularly, especially when starting a new regimen or increasing dosage.
Space out injections to avoid rapid shifts in hormone levels that
may affect vascular tone.
If symptoms persist or worsen, consult a healthcare professional for
evaluation of possible underlying cardiovascular or endocrine causes.
In conclusion, while ipamorelin offers benefits as a growth hormone
secretagogue with a comparatively mild side‑effect profile, long‑term use can still introduce significant health risks.
Understanding the potential hormonal imbalances, cardiovascular changes, metabolic disturbances,
cjc-1295 and ipamorelin side effects specific symptoms such as light‑headedness
is essential for anyone considering this peptide. Regular medical check‑ups, careful dosage management, and attention to early warning signs
will help mitigate these risks and promote safer usage over time.
BPC 157, also known as Body Protective Compound 157, has
rapidly become one of the most talked‑about peptides in sports medicine and regenerative
research circles. This synthetic fragment of a naturally
occurring protein is being studied for its extraordinary
healing properties across a wide range of tissues,
from muscles and tendons to ligaments and even bone.
For athletes who demand fast recovery without compromising
performance, BPC 157 offers a scientific foundation that sets it apart from many other supplements
on the market.
BPC 157 Peptide Benefits
Backed by Science: What Athletes and Researchers Should Know
The evidence for BPC 157’s efficacy comes from an expanding body of pre‑clinical studies, primarily in rodent
models. These investigations consistently show that BPC
157 accelerates tendon repair, reduces inflammation, and improves vascularization. In one
series of experiments, rats with surgically severed
Achilles tendons that received BPC 157 displayed a restoration of normal tensile strength within weeks, whereas untreated
controls required months to reach comparable levels.
Similar results have been observed in ligament healing; the peptide promotes
collagen alignment and enhances fibroblast proliferation, which
translates into stronger, more resilient connective tissue.
Beyond musculoskeletal repair, BPC 157 has demonstrated neuroprotective effects.
Studies involving spinal cord injury models report reduced neuronal loss and improved functional recovery when BPC 157 is administered
early after trauma. The peptide also appears to
modulate the gut‑brain axis; in experimental
colitis, it restores epithelial integrity and dampens systemic inflammation, offering potential benefits for
athletes whose performance can be affected by gastrointestinal distress.
For researchers, one of the most compelling aspects of BPC 157 is its safety profile.
Toxicology studies have shown minimal adverse effects even at high dosages.
The peptide’s stability in physiological conditions means it
can be administered orally or via injection with consistent bioavailability.
Moreover, its mechanism appears to involve upregulation of vascular endothelial growth factor and modulation of the
nitric oxide pathway—both crucial pathways for tissue repair and angiogenesis.
What Makes BPC 157 Unique?
Unlike many other performance‑enhancing substances
that target a single system, BPC 157 is a multi‑target peptide.
Its structure allows it to interact with several cellular receptors simultaneously.
This broad spectrum of action results in synergistic healing: the peptide
not only promotes collagen synthesis but
also reduces oxidative stress and balances inflammatory
cytokines. Because it works at the level of fundamental repair processes, athletes can experience faster return‑to‑play times without relying on anabolic steroids or other drugs that carry significant side effects.
Another distinguishing feature is its compatibility with other
therapeutic regimens. BPC 157 has been combined successfully with platelet‑rich plasma therapies and stem cell
injections in preclinical studies, amplifying the overall regenerative outcome.
Its oral form also offers a convenient option for athletes who prefer not to
use needles; research indicates that the peptide remains active after passage
through the digestive tract, making it one of the few peptides that can be effectively taken by
mouth.
The pharmacokinetics of BPC 157 are favorable as well.
The peptide is rapidly absorbed and distributed throughout the body, reaching peak concentrations within a short period.
It has a relatively long half‑life compared to other small peptides, allowing for less frequent dosing while maintaining therapeutic levels.
This property reduces the risk of compliance issues that often accompany daily
injections or complex supplementation protocols.
Sign up and save!
If you’re an athlete looking to integrate evidence‑based recovery tools into your training routine, consider exploring reputable suppliers
that offer BPC 157 with clear dosage guidelines and quality assurance statements.
Signing up for a subscription can provide consistent
access at discounted rates, ensuring you never
run out during critical healing periods. Many providers also supply detailed usage instructions and support from knowledgeable staff who
understand the nuances of peptide therapy.
In summary, BPC 157 stands out in the peptide landscape because it combines robust scientific backing with a versatile mechanism that supports muscle, tendon, ligament, bone, nerve, and
even gut health. Its safety profile, ease of administration, and compatibility with other regenerative treatments make it an attractive option for athletes and researchers
alike who are committed to optimizing recovery while minimizing risk.
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